Mouse Anti-AD7c Monoclonal Antibody, clone AT1143, det
Order Details
CatNo:
AQSB-060-D
Conjugate:
AQSB-060-D
Size:
1 mg
Product Description
Type:
Antibody Pairs
Clone:
AT1143
Source:
Mouse
Tag:
N/A
Application:
Immunology
ApplicationNote:
Recommended Antibody pairs: ABSQ-060-C-ABSQ-060-D
Description:
Format:
Liquid
Concentration:
Please refer to the vial lable for the specific concentration.
Purification:
Protein A
Buffer:
Supplied in PBS.
Storage:
Short Term: 2-8 degree. Long Term: -48 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. N orthern blot analysis detected 1.4-and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrat ed that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD.