Power Your Research with Abvigen's RNA Catalog
Abvigen delivers a comprehensive range of high-performance RNA products designed to accelerate breakthroughs in gene editing, vaccine development, protein replacement, and therapeutics. Our catalog includes linear mRNA, circular RNA (circRNA), self-amplifying RNA (saRNA), and lipid nanoparticle (LNP) formulations, all optimized for superior expression, stability, and reliability.
Backed by rigorous quality control and expert support, our RNA products are ready to drive your research forward, from basic studies to preclinical applications.
Why Choose Abvigen RNA Products?
Premium Quality: High-purity RNA with over 70 QC assays for consistent performance.
Optimized Expression: Sequence-engineered constructs for maximum protein yield.
Versatile Applications: Ideal for gene editing, vaccines, CAR-T, and protein therapies
Expert Support: Dedicated technical assistance for seamless integration into your workflow.
Our Catalog RNA Product Offerings
Linear mRNA
Precision-engineered for reliable protein expression, our linear mRNA products are sequence-optimized (CDS+UTR) for high performance in gene editing, protein replacement, and vaccine research.
| Product | Applications |
| EGFP mRNA, EGFP mRNA Cy3 Labeled | Fluorescence imaging, gene expression studies |
| Firefly Luciferase mRNA, Renilla Luciferase mRNA, Gaussia Luciferase mRNA | Bioluminescence assays, reporter gene studies |
| mCherry mRNA, mCherry mRNA Cy5 Labeled | Fluorescence imaging, protein tracking |
| CD19 CAR mRNA | CAR-T cell therapy, immunotherapy |
| Human Erythropoietin (EPO) mRNA, Ovalbumin (OVA) mRNA | Protein replacement, vaccine development |
| Cas9 mRNA, Cpf1/Cas12a mRNA, PE2/PE3 mRNA | CRISPR-based gene editing |
| Cre NLS mRNA, Sleeping Beauty mRNA, PiggyBac mRNA | Genome engineering, transposon-based systems |
| Spike mRNA, Beta Galactosidase mRNA | Vaccine research, enzymatic assays |
Self-Amplifying RNA (saRNA)
Our saRNA products deliver potent, sustained protein expression with minimal dosing, ideal for vaccines and advanced therapeutics.
| Product | Applications |
|---|---|
| Firefly Luciferase saRNA | Bioluminescence assays, reporter gene studies |
| EGFP saRNA | Fluorescence imaging, gene expression studies |
| mCherry saRNA | Fluorescence imaging, protein tracking |
Circular RNA (circRNA)
Our circRNA products offer enhanced stability and prolonged expression, perfect for long-term therapeutic applications.
| Product | Applications |
|---|---|
| EGFP circRNA | Fluorescence imaging, stable gene expression |
| FLuc circRNA | Bioluminescence assays, long-term reporter studies |
Lipid Nanoparticle (LNP) Delivery Systems
Our LNP formulations enhance mRNA stability and delivery, offering low immunogenicity and repeat administration capabilities for in vitro and in vivo applications.
| Product | Applications |
|---|---|
| FLuc mRNA-LNP | Bioluminescence assays, in vivo delivery |
| EGFP mRNA-LNP | Fluorescence imaging, in vivo gene expression |
| mCherry mRNA-LNP | Fluorescence imaging, in vivo protein tracking |
Double stranded ds RNA
A critical challenge faced during the development and manufacturing of RNA-based therapies is the presence of unintended impurities, particularly double-stranded RNA (dsRNA). While dsRNA is an inevitable byproduct of the in vitro transcription (IVT) process, unchecked contamination can severely jeopardize both the safety and effectiveness of the treatment.
| Product | Applications |
|---|---|
| dsRNA 500(N1mpU or UTP) | Quality Control |
| dsRNA 1000 (N1mpU or UTP) | Quality Control |
| dsRNA 1500 (N1mpU or UTP) | Quality Contro |
| dsRNA hairpin 70 (N1mpU or UTP) | Quality Control |
Rigorous Quality Control
Every RNA product undergoes over 70 quality control assays to ensure top performance and reliability:
| Attribute | QC Assay | Specification |
|---|---|---|
| Identity | Sanger Sequencing | Matches Target Sequence |
| RNA Length | Capillary Gel Electrophoresis | Target ¡À30% |
| Concentration | UV Spectrophotometry | Target ¡À5% |
| Capping Efficiency | LC-MS | ¡Ý95% |
| Purity (A260/280) | UV Spectrophotometry | 1.8-2.2 |
| Endotoxin | Kinetic Chromogenic Assay | <5 EU/mg |
| Residual dsRNA | Dot Blot Assay | Undetectable |
| Circularization Efficiency (circRNA) | Capillary Gel Electrophoresis | ¡Ý90% |