AAV Service-Abvigen Inc

Protein Platform
- Protein Expression
  - --|--|E. Coli Expression
  - --|--|Yeast Expression
  - --|--| Baculovirus-Insect Expression
  - --|--|Mammalian Expression
  - --|--|Large-Scale Protein Production
  - --|--|PEGylation
  - --|--|Serum-Free Protein Expression
  - --|--|SUMO-Tag Protein Production
  - --|--|Endotoxin-Free Protein Production
  - --|--|Stable Cell Line Construction
- Protein Conjugation
  - --|--|Protein Conjugation
  - --|--|Colloidal Gold Conjugation
  - --|--|Nucleic Acid Labeling
  - --|--|Magnetic Beads Conjugation
- Proteomics
  - --|--|Edman SequencingN-terminal Sequencing-Edman
  - --|--|N-terminal Sequencing-MS
  - --|--|ITRAQ/ TMT Labeling Quantitative
  - --|--|Label Free
  - --|--|Peptide Coverage
  - --|--|Amino Acid Sequencing
Antibody Platform
- Monoclonal Antibody
  - --|--|Mouse Monoclonal Antibody Production
  - --|--|Rabbit Monoclonal Antibody Production
  - --|--|Small Molecule Monoclonal Antibody Production
  - --|--|Membrane Protein Antibody Production
  - --|--|Methylated Monoclonal Antibody Production
  - --|--|Acetylated Monoclonal Antibody Production
- Polyclonal Antibody
  - --|--|Mouse Polyclonal Antibody Production
  - --|--|Rabbit Polyclonal Antibody Production
  - --|--|Rat Polyclonal Antibody Production
  - --|--|Sheep Polyclonal Antibody Production
  - --|--|Chicken Polyclonal Antibody Production
  - --|--|Guinea Pig Polyclonal Antibody Production
- Recombinant Antibody
  - --|--|Recombinant Antibody Production
- Antibody Sequencing
  - --|--|Hybridoma Sequencing
  - --|--|Single Cell Transcriptome Sequencing
- Modified Antibody
  - --|--|Phosphorylated Monoclonal Antibody Production
- Antibody Engineering
  - --|--|Scale-up Antibody Production
  - --|--|Anti-idiotypic Antibody Production
  - --|--|Antibody Affinity Determination
  - --|--|DNA Immunization
  - --|--|Stable Cell Line Construction
  - --|--|Single B Cell Antibody Development
Peptide Platform
Other Services
- Customized magnetic bead
- AAV Service

Adeno-Associated Virus Service

AAV belongs to the genus Dependoparvovirus. It is one of the smallest viruses with a non-enveloped capsid of approximately 22 nm that infect a broad range of cell types including dividing and non-dividing cells and are, therefore, widely used vehicles for gene delivery.

Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell. It makes AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models.

Different serotypes can render the virus with different tissue tropism. Tissue specificity is determined by the capsid serotype.

Abvigen has developed the most robust and professional AAV packaging service, offering the highest quality rAAV vectors and the most complete AAV Expression Systems that can be used to express shRNA, human ORF, CRISPR in vitro and in vivo studies.

Cloning

Transfection

Packaging:

Small Scale Crude Packaging

Large Scale Packaging, in vivo ready

Purification For large scale

Quality control

AAV particles

AAV Service.jpg

Advantages

High titer

Safest viral vector system available

Effectiveness in vitro and in vivo

No inflammation

Causing no known human disease