Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Buffer:
Supplied in PBS.
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
Synonyms:
GAB2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; Grb2 associated binder 2; KIAA0571; pp100; Grb2-associated binder 2; growth factor receptor bound protein 2-associated protein 2
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