Its activity was determined in human T lymphocytes by measuring its ability to inhibit IL-2 secretion induced by anti-CD3 monoclonal antibodies, with ED50 ranging from 1 to 6ug/mL.
Format:
Lyophilized powder
Purity:
≥95%, SDS-PAGE
Concentration:
Please refer to the vial lable for the specific concentration.
Purification:
Chromatography
Molecular Weight:
19.8kD
Buffer:
Supplied in PBS with 6% Mannitol, pH7.4.
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
V-type immunoglobulin domain-containing suppressor of T-cell activation(VISTA) also known as platelet receptor Gi24 , stress-induced secreted protein-1 (Sisp-1) and B7.
Synonyms:
B7-H5; B7H5; C10orf54; DD1alpha; GI24; PD-1H; PP2135; SISP1; VISTA