Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Molecular Weight:
19 kDa
Immunogen:
LIGHT/TNFSF14
Buffer:
Supplied in PBS
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
Tumor necrosis factor superfamily member 14 (TNFSF14), LIGHT, is a component of the cytokine network that regulates innate and adaptive immune responses, which promote homeostasis of lymphoid organs, liver, and bone. TNFSF14 is an immunomodulatory cytokine and a member of the TNF superfamily. It is expressed by lymphocytes, monocytes, and granulocytes, and is primarily known for its critical role in immune functions. TNFSF14 leads to T cell activation through interaction with HVEM by enhancing T cell proliferation and induces cytokine secretion through binding to lymphotoxin β receptor (LTβR) on mast cells. TNFSF14 has also been implicated in various pathogenic conditions related to inflammatory responses such as tumors, type 2 diabetes, and atherosclerosis.
Synonyms:
CD258, HVEML, HVEM-L, LIGHT, LTg, TNFSF14, TR2
Note
For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
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info@abvigenus.com