Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Molecular Weight:
45.4 kDa
Immunogen:
4-1BB Ligand/TNFSF9
Buffer:
Supplied in PBS
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
TNFSF9 (Tumor necrosis factor ligand superfamilymember 9) is also known as 4-1BBL (4-1BB ligand) or CD137L. TNFSF9 is a type 2 transmembrane glycoprotein receptor that is found on APCs (antigen presenting cells). TNFSF9 is expressed on activated T Lymphocytes. The TNFSF9/4-1BB complexwith the help of T-cell receptorsignals can trigger the increase in CD28? T cells and inhibit tumor growth. The interaction between 4-1BB and TNFSF9 provides costimulatory signals to T cells, which can be used to cancer immunotherapy.
Synonyms:
4-1BB Ligand, 4-1BBL, CD137L, TNFSF9
Note
For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
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