Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Molecular Weight:
16.3 kDa
Immunogen:
IL-2
Buffer:
Supplied in PBS
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
IL-2 (Interleukin-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It regulates white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. The major sources of IL-2 are activated CD4+ T cells and activated CD8+ T cells. IL-2 mediates its effects by binding to IL-2 receptors which are expressed by lymphocytes. IL-2 signal can be transduced by 3 different signaling pathways: JAK/STAT, PI3K/Akt/mTOR and MAPK/ERK pathway. IL-2 plays a role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. It also promotes proliferation of activated B cells and subsequently immunoglobulin production.
Synonyms:
IL-2, Interleukin 2, Lymphokine, TCGF
Note
For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
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