Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Molecular Weight:
110.3 kDa
Immunogen:
VEGFR2/KDR
Buffer:
Supplied in PBS
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
VEGFR2, also named as KDR, FLK1 and CD309, is one of the two tyrosine kinase receptors involved in angiogenesis. VEGFR2 is mainly distributed in vascular endothelial cells, lymphatic endothelial cells, and embryonic precursor cells, and can bind to VEGF-A, VEGF-C, and VEGF-D. When activated by its ligand VEGF, VEGFR2 promotes neighbouring vessel formation to facilitate the delivery of growth factors, nutrients and oxygen for cancer proliferation, migration, metastasis and survival. VEGF and VEGFR2 mediated angiogenesis contributes to the aggressive natures and leads to high mortality rate in gastric cancer.
Synonyms:
CD309, FLK1, Flk-1, KDR, KRD1, VEGFR, VEGFR2
Note
For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
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