Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Molecular Weight:
22.5 kDa
Immunogen:
ULBP2
Buffer:
Supplied in PBS
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
NKG2D is an activating cell surface receptor that is predominantly expressed on cytotoxic immune cells. NKG2D recognizes a wide range of ligands. In humans, the NKG2D ligand (NKG2DL) includes MICA, MICB, and six members of the ULBP family (ULBP1-6). ULBPs are MHC class I-related molecules. ULBP2 contains two Ig-like domains, the alpha-1 and alpha-2 domains characteristic of the MHC class I family, but lacks the alpha-3 domain. It can be expressed as either a transmembrane or GPI-linked protein, or released from the cell surface. ULBP2 binds and activates the NKG2D, mediating the recruitment and activation of NK cells.
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