Recombinant Human FGFR3(IIIb) protein, Fc, Myc, His
Order Details
CatNo:
ADMD-066
Conjugate:
ADMD-066
Size:
1mg
Product Description
Type:
Recombinant Proteins
Source:
HEK293
Species:
Human
Tag:
Fc, Myc, His
Application:
Immunology
Description:
Format:
Liquid
Concentration:
Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Molecular Weight:
67.1 kDa
Immunogen:
FGFR3(IIIb)
Buffer:
Supplied in PBS
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
FGFR3 (Fibroblast growth factor receptor 3) is a tyrosine-protein kinase that that acts as cell-surface receptor for fibroblast growth factors. FGFR3 binds acidic and basic fibroblast GH and plays important roles in development, osteogenesis, and bone maintenance. FGFR3 is highly expressed in chondrocytes and osteoblasts, and germline mutations are associated with bone growth disorders such as achondroplasia, chondrodysplasia, and thanatophoric dysplasia. Due to frequent mutations in certain cancers, FGFR3 gene has also been associated with tumor progression.
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