Recombinant Human FGFR2(IIIc) protein, Fc, Myc, His
Order Details
CatNo:
ADMD-065
Conjugate:
ADMD-065
Size:
1mg
Product Description
Type:
Recombinant Proteins
Source:
HEK293
Species:
Human
Tag:
Fc, Myc, His
Application:
Immunology
Description:
Format:
Liquid
Concentration:
Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Molecular Weight:
68 kDa
Immunogen:
FGFR2(IIIc)
Buffer:
Supplied in PBS
Storage:
Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.
General Information
Background:
FGFR2 (Fibroblast growth factor receptor 2) is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis. Ligand binding leads to the activation of several signaling pathway, such as RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP Kinase signaling pathway, as well as the AKT1 signaling pathway. Mutations in the gene of FGFR2 are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis.
Synonyms:
FGFR2, FGFR2 (IIIc)
Note
For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals.
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