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Rabbit Anti-ADAM15 PAb

Product Description

  • Type:
  • Polyclonal Antibody
  • Source:
  • Rabbit
  • Species:
  • Human
  • Application:
  • ELISA; WB; IHC
  • Description:
  • Swissprot Q13444; Gene Accession BC014566
  • Format:
  • Liquid
  • Concentration:
  • Please refer to the vial lable for the specific concentration.
  • Purification:
  • Protein A/G
  • Buffer:
  • Supplied in PBS.
  • Storage:
  • Short Term: 2-8 degree. Long Term: -20 degree. Avoid multiple freeze-thaw cycles.

General Information

  • Background:
  • The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
  • Synonyms:
  • MDC15; ADAM metallopeptidase domain 15; ADAM 15

Documents

Order Details

Cat No:ABSPA-0393

Conjugate:ABSPA-0393

Size:1 mg

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  • info@abvigenus.com