Please refer to the vial lable for the specific concentration.
Purification:
Protein A/G
Buffer:
Supplied in 0.01 M PBS; pH 7.4.
Storage:
Store at -20 degree for long term.
General Information
Background:
There are four subtypes of IgG antibodies: IgG1, IgG2, IgG3, IgG4. Although the position and number of disulfide bonds are different, the spatial structure of the four subtypes of IgG antibodies is very similar, and the content decreases in turn. IgG3 has an extended hinge area, and its core hinge area has 11 pairs of disulfide bonds, so it is unstable for protease cutting. IgG3 and Fc γ The binding capacity of Rs is the strongest, which can trigger ADCC and ADCP, and the CDC effect is stronger than IgG1. But the half-life of IgG3 is shorter.
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